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This chart shows levels of SARS-CoV-2 and deactivated YAP (pYAP127) in healthy cultured cells (mock) and cultured cells infected with the original strain of COVID-19 (SARS-CoV-2 Parental) and the Delta strain (SARS-CoV-2 Delta). Asterisks in the insets indicate uninfected cells.
From left: Vaithilingaraja Arumugaswami, Nikhil Chakravarty and Gustavo Garcia, Jr.
Group photo of scientists.
Headshot of Brigitte Gomperts
Steps of a virus growth cycle illustration.
Heart muscle cells in an uninfected mouse (left) and a mouse infected with SARS-CoV-2 (right) with mitochondria seen in pink. The disorganization of the cells and mitochondria in the image at right is associated with irregular heartbeat and death.
Microscopic images of human stem cell–derived airway tissue models with cell nuclei (blue) and SARS-CoV-2 virus infected cells (green); tissue exposed to cigarette smoke (right) had 2 to 3 times more infected cells than non-exposed tissue (left).
Human induced pluripotent stem cell-derived cardiomyocytes (heart cells) shown in green and blue, are infected by the novel coronavirus SARS-CoV-2 (red)