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Dr. Brigitte Gomperts, Dr. Siavash Kurdistani and William Lowry have been appointed associate directors of the UCLA Broad Stem Cell Research Center.
Group photo of scientists.
Headshot of Brigitte Gomperts
Healthy airways (left) show well-defined layers of ciliated cells (green) and basal stem cells (red). In airways affected by cystic fibrosis (right), the layers are disrupted, and scientists identified a transitioning cell type that combines properties of both stem cells and ciliated cells (red and green in the same cell).
Microscopic images of human stem cell–derived airway tissue models with cell nuclei (blue) and SARS-CoV-2 virus infected cells (green); tissue exposed to cigarette smoke (right) had 2 to 3 times more infected cells than non-exposed tissue (left).
Microscopic image showing stem cells in young (left) and old (right) airways with cell nuclei seen in blue, airway basal stem cells seen in red and ciliated cells seen in green.
Normal airway tissue, left, and lung cancer tissue, right, with an overabundance of basal stem cells (green). The activated form of beta-catenin (red) in the lung cancer can be targeted by the Wnt Inhibitor Compound 1.
Microscopic image of scarring in a dish, showing evidence of fibrosis (red, green) and nuclei of all cells (blue).