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Microscope image of dendritic cells produced from blood-forming stem cells. Dr. Christopher Seet, top right, and Dr. Gay Crooks.
Differentiating human pluripotent stem cells (blue) turning into human germ cells (pink and white).
Microscopic image of scarring in a dish, showing evidence of fibrosis (red, green) and nuclei of all cells (blue).
Research by UCLA’s Gay Crooks, Amélie Montel-Hagen and Christopher Seet could point the way toward “off-the-shelf” T cell therapies that are more readily available to patients.
Expression of pleiotrophin (green) in bone marrow blood vessels (red) and stromal cells (white) is shown in normal mice (left) and in mice at 24 hours following irradiation (right).
Left: Olig2 expression (blue) results in reduced Hes gene expression (red) and increased motor neuron formation (green) in the developing mouse spinal cord. Right: in the absence of Olig2, Hes expression increases and motor neuron formation decreases.
Dr. Joanna Gell (left) and Amander Clark examine germ cell tumor cells in the lab at UCLA.
Human embryonic stem cell-derived neurons (green) showing nuclei in blue. Left: with retinoic acid added. Right: with retinoic acid and BMP4 added, creating proprioceptive sensory interneurons (pink).
Skeletal muscle cells isolated using the ERBB3 and NGFR surface markers (right) restore human dystrophin (green) after transplantation significantly greater than previous methods (left).