CELEBRATING 20 YEARS OF TRANSFORMATIVE STEM CELL RESEARCH
DIVE INTO THE DIGITAL REPORT

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Immunofluorescent staining demonstrating fibroblasts expressing the Channelrhodopsin protein in heart scar tissue. The ChR2-expressing fibroblast (green) is in close proximity to cardiomyocytes (red) within scar.
Microscopic images showing heart tissue in mice (with cardiac muscle cells in red) after a heart attack. Untreated tissue (left) shows more DNA damage (green) than tissue that has been treated with an experimental drug (right).
Healthy airways (left) show well-defined layers of ciliated cells (green) and basal stem cells (red). In airways affected by cystic fibrosis (right), the layers are disrupted, and scientists identified a transitioning cell type that combines properties of both stem cells and ciliated cells (red and green in the same cell).
Microscopic images of human stem cell–derived airway tissue models with cell nuclei (blue) and SARS-CoV-2 virus infected cells (green); tissue exposed to cigarette smoke (right) had 2 to 3 times more infected cells than non-exposed tissue (left).
Microscopic image showing stem cells in young (left) and old (right) airways with cell nuclei seen in blue, airway basal stem cells seen in red and ciliated cells seen in green.
Electron microscopy images showing a healthy scar containing collagen type 5 with scar fibers smoothly arranged in parallel (left) and unhealthy scar containing no collagen type 5 with a disorganized architecture with disarray of scar fibers (right).
Human induced pluripotent stem cell-derived cardiomyocytes (heart cells) shown in green and blue, are infected by the novel coronavirus SARS-CoV-2 (red)
Normal airway tissue, left, and lung cancer tissue, right, with an overabundance of basal stem cells (green). The activated form of beta-catenin (red) in the lung cancer can be targeted by the Wnt Inhibitor Compound 1.